The very first Club Health conference was held in the world famous Cream nightclub, Liverpool in 1997. Following the success of the event, The 1st International Conference on Nightlife, Substance Use and Related Health Issues was held in Amsterdam in 1999. Club Health conferences have since been held bi-annually in Australia, North America and throughout Europe. The 12th International Conference on Nightlife, Substance Use and Related Health Issues returns to Liverpool in November 2023.